DataSHIELD beginners' workshop @ UMCG (optional, supplementary fee)

Tutors:

• Tim Cadman, University of Copenhagen
• Angela Pinot de Moira, Imperial College London
• Andrei Morgan, INSERM
• Juan Ramón González, ISGlobal
• Demetris Avraam, University of Liverpool

This workshop will begin with a 30-minute introductory talk about DataSHIELD, including how it works and how it facilitates data sharing. This will be followed by a hands-on practical where participants will learn how to assign data from Opal and Armadillo servers, carry out basic data manipulations such as reshaping and merging dataframes, subsetting data and creating new variables and perform some simple data analysis.

Registration and lunch (joint with the EUCAN-Connect Consortium)

Welcome Morris Swertz, UMGC and Andrei Morgan, INSERM

DataSHIELD Software Compliance and Audit Discussion (Moderator Andrei Morgan)

• DataSHIELD disclosure risk response.  Becca Wilson, University of Liverpool 
• DataSHIELD software audit process. Tom Bishop, University of Cambridge

Discussion time: 45 minutes

DataSHIELD Infrastructure Updates

• dsBase upcoming release - Stuart Wheater, Arjuna Technologies
• Opal Update - Yannick Marcon, Epigeny
• Molgenis Update - Morris Swertz, UMGC 

Coffee Break

DataSHIELD Community Session

• Updates from the DataSHIELD Steering Committee
• Updates from the DataSHIELD Advisory Board

Registration and coffee

Welcome 

Keynote talk
Personal Health Train (title to be confirmed). Gijs Geleijnse, IKNL

Coffee break

Machine Learning

• Talk: Federated Non-Linear Mixed-Effect Modelling in DataSHIELD using Julia. Manuel Huth, Helmholtz Munich
• Talk: A Versatile DataSHIELD Package for Lung CT Scan Analysis and Beyond. Juan R Gonzalez, ISGlobal
• Talk: dsMatchIt: Federated Matching Methods for Covariate Balancing. Roy Gusinow, Helmholtz Munich
• Talk: New DataSHIELD functions from the dsClusterAnalysis and dsIntestinalMicrobiomics packages. Florian Schwarz, German Institute of Human Nutrition Potsdam-Rehbruecke
• Panel Discussion: Machine Learning (all speakers) 

Lunch

Omics 

• Talk: Enabling Federated Multi-Omics Analysis on Virtual Cohorts. Mark Ibberson, Swiss Institute of Bioinformatics
• Talk: Using DataSHIELD to examine the association between body mass index and gut microbiota composition among adults from multiple European observational studies. Carolina Schwedhelm, Max Delbrück Centre for Molecular Medicine

Infrastructure I

• Lightning Talk: Why not DataSHIELD with Ansible? - Ahmet Akkoc, Zitelab Aps
• Lightning Talk: Addressing Scalability Challenges and Enhancing User Experience in DataSHIELD: Implementation of an Identity and Access Management and Central R Server. Sofia Maria Siampani, Max Delbrück Centre for Molecular Medicine 
• Lightning Talk: Harmonization of gut microbiome data from multiple European observational studies using a common bioinformatics pipeline: from raw data to harmonized data for analysis with DataSHIELD. Carolina Schwedhelm, Max Delbrück Centre for Molecular Medicine 

Coffee Break

Infrastructure II

• Talk: DataSHIELD Analysis in Python. Yannick Marcon, Epigeny
• Talk: Integrating DataSHIELD with OMOP CDM: A Novel Approach for Efficient Data Sharing and Analysis of Harmonized and Standardized Clinical Data. David Sarrat González, ISGlobal

Closing Talk
Join the DataSHIELD train - but how far away is the station? Bodil Svenblad, Uppsala University

Among analysts without experience of federated analysis the concept is often met with interest, curiosity, skepticism and hesitation. The infrastructure SIMPLER can offer federated analysis as a tool – but researchers are hesitant to use it. The Swedish Medical Products Agency has reported on the concept, the technical requirements and the analysis methods currently implemented with the aim of investigating whether Federated Analysis is a possible tool to use for structured follow-ups of pharmaceuticals. In this talk I will describe the projects, the response and questions we get when presenting the concept for an unexperienced audience together with my personal thoughts about how the way to the station where one can hop on the DataSHIELD train looks like today– and whether it is possible to find a shortcut.

Drinks reception and networking

Conference Dinner 
Cafe Willem Albert

Welcome

Keynote Talk
NFDI4Health - Building up a national research data infrastructure for personal health data  Tobias Pischon, Max Delbrück Center for Molecular Medicine

Coffee break

Longitudinal Data

• Talk: Legal Review of DataSHIELD (Title TBC). Fruzsina Molnár-Gábor, Heidleberg University
• Talk: Does federated analytics preserve statistical and scientific value of real world data? David Pau, Roche
• Lightning Talk: Enhancing Survival Analysis with survival tables. Xavier Escribà Montagut, IS Global
• Talk: Survival according to sex at birth among extremely preterm fetuses: a pan-European study from the RECAP Preterm platform of cohort and register data. Andrei Morgan, INSERM
• Lightning Talk: Long term Follow-up after Trials Using a European Platform of Preterm birth cohorts – the LIFT-UP Preterm study protocol. Andrei Morgan, INSERM
• Talk: DARAH Project -  deploying a DataSHIELD federated network in real world healthcare environments. Camille Bachot, Roche
• Panel Discussion (All speakers)

Closing remarks. Morris Swertz, UMCG

Lunch