16 November 2023

08:45 - 09:30

Registration &
coffee at Villa Jongerius

09:30 - 09:45

Welcome

09:45 - 11:00

Lipidomics & Fluxomics 

Session chair: Martin Giera, LUMC

Keynote: Craig Wheelock, Karolinska Institute, SE

"Not just fat" – Exploring Octadecanoids as Novel Bioactive Lipids in Inflammation.

Diana Ilyaskina

Lipidomics approach to study Lipid metabolism of Springtails Folsomia candida in Response to the Growth Inhibitor Insecticide Teflubenzuron over time

Ting Zeng

Ion Mobility Mass Spectrometry-based Untargeted Serum Lipidomics Characterization in the General Chinese Cohort with Residual Per-/Polyfluoroalkyl Substances

Fenne Verheijen

TolDCs show dependency on glutamate-glutamine axis to drive TCA cycle metabolism

11:00 - 11:30

Coffee break

11:30 - 12:45

Metabolomics: Biomedical Application-1

Session chair:  Esther Zaal

Martin Giera, Leiden University Medical Centre, NL 

A lipidomics view on neurodegeneration. 

Kimberly De Windt

Advancing Pediatric Precision Healthcare: Integrating Rapid Metabotyping as a Fundamental Component for 4P Medicine.

Wei Yang

Association of oxidative stress and inflammatory metabolites with Alzheimer’s disease cerebrospinal fluid biomarkers in mild cognitive impairment.

Demi Rijlaarsdam

Identifying metabolic crosstalk between hepatic stellate cells and hepatocellular carcinoma cells,

12:45 - 13:30

LUNCH 

13:30 - 14:15

POSTERS and STANDS

14:15 - 15:15

Metabolite identification & New Analytical Developments

Session chair: Leon Coulier

Xavier Domingo, Eurecat - Technology Centre of Catalonia, SP

Annotating untargeted metabolomics data: have we overcome the featuromics era?

Nicolas de Fooz

Universal at-line microbial fermentation monitoring through advances in rapid ambient ionisation mass spectrometry-based metabolomics

Fien Verdoodt

Canine cerebrospinal fluid metabolomics: an optimized extraction method for liquid chromatography coupled to mass spectrometry (UHPLC-HRMS)

 

15:15 - 15:45

Coffee break

15:45 - 17:00

Computational Metabolomics

Session chair: Leon Coulier

Peter Horvatovich, UMCG, NL 

Tools and algorithms to improve quantification of metabolite in LC-MS/MS data 

Kevin Mildau

Tailored mass spectral data exploration using the specXplore interactive dashboard.

Jung-Chin Chang

MASH-in-a-dish: Identifying targetable metabolite crosstalk for MASH treatment.

Daniëlle Gramsbergen

Investigating the link between NAD metabolism and oxidative stress using kinetic modelling.

17:00 - 17:15

YoungNMC Presentation and Drinks

17:30 - 20:00

Conference dinner at Villa Jongerius

17 November 2023

08:30 - 09:00

Registration & coffee at Jaarbeurs Utrecht

09:00 - 09:15

Welcome

09:15 - 10:00

Alison HeppenstallUniversity of Glasgow, Scotland, UK & Gary PolhillThe James Hutton Institute, Scotland, UK

Challenges and opportunities of using ABMs for simulating social systems

10:00 - 10:30

Coffee break

10:30 - 11:30

Environmental Metabolomics - 1

Session chair: Thomas Hankemeier

Elliott Price, RECETOX, Masaryk University, CZ 

Scaling characterisation of human exposure to chemicals

Carmen Bedia, Idaea, Barcelona, Spain

Integrated new approach methodologies to study the effects of airborne pollution on lung health: application to air samples from suburban and rural backgrounds

 

11:30 - 12:30

In depth session -
Environmental Metabolomics - 2

Session chair: Thomas Hankemeier

Manuel Garcia-Jaramillo

Using Multi-Omics Analysis to Investigate the Toxicity of Road Runoff Water-Derived Contaminants in Juvenile Salmonid Species

Lackson Kashobwe

Application of Lipidomics in unveiling the impact of PFAS and Alternative on lipid metabolism and composition: Insights from an In Vitro Human Hepatocyte Model

Lieselot Y. Hemeryck

Upscaling sample preparation, analysis and data preprocessing in DNA adductomics for large-scale exposomics

Maria van de Lavoir

Unlocking the past: exploring untargeted hair lipidomics for retrospective analysis

12:30 - 14:00

Lunch & posters, stands

14:00 - 14:45

Cathryn Tonne, ISGlobal, Spain

Exposome-based interventions to promote healthy urban environments

14:45 - 15:00

Poster Prizes & Coffee break 

15:00 - 16:00

Spatial Metabolomics /
Food & Nutrition

Session chair: Esther Zaal

Leon Coulier DSM Firmenich

Industrial challenges in food and microbial metabolomics. 

Melanie Planque, KU Leuven, BE 

Spatial distribution of metabolites and lipids in tumor and metastatic cancer tissues by MALDI and DESI mass spectrometry imaging.

 

16:00 - 17:00

In depth session - 
Biomedical application 

 

Session chair: Leon Coulier

Victoria Pozo Garcia

Central carbon metabolism characterization of iPSC-derived hepatocytes.

Joshua Bekman

Tiered in silico approach to identify the taste of peptides

 

Ellen Van den Broecke

Urine and serum metabolomics in veterinary medicine: towards early diagnosis of feline chronic kidney disease.

Ali Dehghani

Synbiotics, a promising approach to reduce the exacerbated allergic airway immune responses in offspring maternally exposed to cigarette smoke.

 

17:00 - 18:00

Closing, drinks & bites

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