| MAY 30 | |||
| Introduction | 09:15 | Marije Bartels / Pierre-Emmanuel Gleizes | |
| Basic and translational research 1 | 09:25 | Andrea Ditadi | - A view of human hematopoietic development and disease from the Petri dish |
| 09:45 | Dorine Swinkels | - Pathophysiology and diagnosis of iron overload and toxicity in DBA | |
| 10:05 | Emile van den Akker | - Towards transfusion-ready red blood cells from induced pluripotent stem cells (iPSCs) | |
| Coffee break | 10:25 | - 11:00 | |
| Basic and translational research 2 | 11:00 | Marie-Françoise O'Donohue | - HEATR3 variants impair nuclear import of uL18 (RPL5) and drive Diamond-Blackfan anemia |
| 11:20 | Marc Baud'huin | - RPL13 mutation causes an acceleration of mesenchymal stem cell chondrogenic differentiation to the hypertrophic stage | |
| 11:40 | Alan Warren | - Convergent somatic evolution from early life in a germline ribosomopathy | |
| Lunch | 12:00 | - 13:00 | |
| Keynote lectures | 13:00 | Steve Ellis (Landsteiner lecture) | - Diamond Blackfan anemia and cancer predisposition: more questions than answers |
| 13:30 | Elspeth Payne | - High content zebrafish screens in ribosome protein mediated disorders | |
| Innovative therapies and new treatments 1 | 14:05 | Stefan Karlsson | - Development of gene therapy for Diamond Blackfan anemia |
| 14:25 | Susanna Navarro | - En route to lentiviral gene therapy for RPS19-Diamond Blackfan anemia patients | |
| 14:45 | Johan Flygare | - CDK8/19 inhibitor RVU120 (SEL120) - a Diamond-Blackfan anemia drug candidate | |
| Coffee Break | 15:05 | - 15:40 | |
| Innovative therapies and new treatments 2 | 15:40 | Brigitte Strahm | - HSCT in children and adolescents with Diamond-Blackfan anemia |
| 16:00 | Jeffrey Lipton | - Cancer and Diamond Blackfan anemia (DBA) syndrome: Time to seize the opportunity | |
| 16:20 | Alexander Puzik | - When children grow up: what do we know about the medical needs of adult patients with Diamond Blackfan anemia | |
| 16:40 | Antonis Kattamis | - Iron overload in Diamond-Blackfan anemia | |
| 17:00 | Thierry Leblanc | - Diagnosing and treating Diamond Blackfan Anemia Syndrome: results of a second international consensus conference | |
| Break | 17:20 | - 17:40 | |
| Short talks | 17:40 | Ayse Gurel | - Duplication of RPL5 indicates “imbalance-of-function” as a novel mechanism in DBA |
| 17:52 | Simon Lebaron | - NSCP1, a new player in nucleolar stress resistance | |
| 18:04 | Nesligul Hasibe Gonen | - Somatic 5q deletion: a molecular diagnostic challenge in Diamond-Blackfan Anemia | |
| Buffet | 18:45 | - 21:00 | Meet and greet with the patient representatives |
| MAY 31 | |||
| DBA registries and new cases 1 |
09:00 | Kaan Boztug | - Strategies of NGS data analysis to maximize efficiency of identification of causative gene defects in non-malignant hematological diseases and inherited bone marrow failure syndromes |
| 09:20 | Marije Bartels | - The power of patient registries : the EuroDBA experience | |
| 09:40 | Paola Quarello | - Osteosarcoma in Italian DBA patients: epidemiology and preliminary data on genomic somatic analysis | |
| 10:00 | Galina Ovsyannikova | - The rare cases of “Diamond-Blackfan anemia phenocopies”: a report from the Russian DBA registry | |
| 10:15 | Amir Hamidieh |
- The HSCT outcome update of seventeen Iranian DBA patients conditioned with a non-radiation myeloablative regimen
|
|
| Coffee break | 10:30 | - 11:05 | |
| DBA registries and new cases 2 | 11:05 | Adrianna Vlachos | - An update from the Diamond Blackfan anemia registry of North America |
| 11:25 | Dagmar Pospisilova | - Clinical and selected laboratory characteristics of patients enrolled in the Czech and Slovak Diamond-Blackfan anemia Registry | |
| 11:40 | Arda Cetinkaya | - Diamond-Blackfan Anemia from a Recessive Perspective | |
| Lunch | 12:00 | - 13:15 | |
| Keynote lecture | 13:15 | Lionel Blanc | - Stage-specific hematopoietic failure in a novel model of Diamond Blackfan anemia |
| Basic and translational research 3 | 13:45 | Devon Germain | - Characterization of Diamond-Blackfan Anemia patients and silent carriers via erythroid differentiation |
| 14:05 | Senthil Bhoopalan | - TP53-dependent hematopoietic stem cell defect in a novel CRISPR/Cas9-based model of DBA | |
| 14:25 | Yang Liu | - Therapeutic effects and single-cell profiling of a clinically applicable lentiviral vector for Diamond-blackfan anemia in human RPS19-deficient CD34+ hematopoietic progenitor and stem cells | |
| 14:45 | Jakob Berner | - HPO annotation and network analysis in Diamond-Blackfan Anemia | |
| Closing remarks | 15:05 | Marcel Hibert | - Closing remarks from a PAO perspective |
Global Bridges 2022
Registration website for Global Bridges 2022Global Bridges 2022globalbridges2022@gmail.com
Global Bridges 2022globalbridges2022@gmail.comhttps://www.aanmelder.nl/131965
2022-05-30
2022-05-31
OfflineEventAttendanceMode
EventScheduled
Global Bridges 2022Global Bridges 20220.00EUROnlineOnly2019-01-01T00:00:00Z
Sanquin ResearchSanquin ResearchPlesmanlaan 125 1066 CX Amsterdam Netherlands
Powered by
event registration made easy
event registration made easy
aanmelder.nl is the software partner for events.
Click here to discover the software.